Free Radical Theory of Aging at 70: Adaptive Homeostasis and the Modern Revision of a Classic Hypothesis
Mueen Ahmed KK
Denham Harman’s free radical theory of aging, first articulated in the mid-1950s, proposed an elegantly simple mechanism for senescence: metabolism generates reactive byproducts, those byproducts accumulate as molecular damage, and accumulated damage is aging. Seven decades on, the theory remains one of the most cited frameworks in biogerontology, but its core causal claim has been substantially reworked rather than confirmed.
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4H-Pyran-4-One (γ-Pyrone): Structure, Electronic Character, Spectrochemical Signature, and Pharmaceutical Relevance of a Privileged Heterocyclic Scaffold
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Should Antioxidant Supplementation Be Contraindicated During Active Cancer Treatment?
Mohammed Yunus
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