@article{Jeyapragash_Subhashini_Raja_Abirami_Thangaradjou_2015, title={Evaluation of In-vitro Antioxidant Activity of Seagrasses: Signals for Potential Alternate Source}, volume={6}, url={https://www.antiox.org/index.php/fra/article/view/67}, DOI={10.5530/fra.2016.1.10}, abstractNote={<p><strong>Background and Aim:</strong> Natural antioxidants have gained unique attention in recent years. Because of the carcinogenicity of synthetic compounds, there is a dearth for antioxidants from natural origin. Currently, seagrasses, the marine plants have gained attention for their secondary metabolites. Hence, the present study aims to examine <em>in vitro</em> antioxidant activity of both leaf and rhizome extracts of six seagrass species and has not yet been investigated.<strong> Methods:</strong> Crude methanolic extracts of leaf and rhizome obtained, were evaluated for total phenolic contents using Folin-Ciocalteaus method. Antioxidant potential of seagrass extracts were evaluated using total antioxidant activity, DPPH, FRAP, ABTS assay, H<sub>2</sub>O<sub>2</sub> and NO<sub>2</sub> scavenging assay and the phenolic compounds present in potent extracts were profiled by HPLC. <strong>Results:</strong> Maximum phenolic content and antioxidant activity was exhibited by leaf and rhizome extracts of <em>C. rotundata</em> followed by<em> H. uninervis.</em> Higher DPPH radical scavenging activity was found in leaf (78.84 ± 0.87) and rhizome extracts (75.480 ± 0.97) of <em>C. rotundata</em> and the lowest scavenging activity was found in the leaf and rhizome extracts of H. ovata (12.01 ± 0.63 and 5.769 ± 1.14). Among six species, <em>C. rotundata</em> exhibited higher radical scavenging activity containing the potential phenolic compounds.<strong> Conclusion:</strong> Present study portrays that leaf and rhizome extracts of <em>C. rotundata</em> acts as a potential source of antioxidant compounds with predominant presence of caffeic acid and ρ-coumaric acid that paves a way for the application of these compounds in both food and pharmaceutical industries as a multipotent antioxidant.</p>}, number={1}, journal={Free Radicals and Antioxidants}, author={Jeyapragash, Danaraj and Subhashini, Ponnnambalam and Raja, Subramaniyan and Abirami, Karmegam and Thangaradjou, Thirunavukarassu}, year={2015}, month={Aug.}, pages={77–89} }