@article{Ahmad Tantry_Ahmad Wani_2021, title={RETRACTED: Effects of Grape Seed Extract Supplementation and Physical Activity on Skeletal Muscle of Male Albino Rat}, volume={10}, url={https://www.antiox.org/index.php/fra/article/view/293}, DOI={10.5530/fra.2020.2.13}, abstractNote={<p style="text-align: justify;"><strong>Objectives: </strong>This study investigated the effect of grape seed extract on swim exercise and oxidative stress in acute and chronically exercised rats.<strong> Methods:</strong> This study was attempted on one month old male albino Wistar rats. Rats were exposed to swim exercise daily for duration of 30 min Day-1. During the experiment estimation of blood parameters, lipid profile, antioxidant enzymes and oxidative stress parameters were evaluated. <strong>Results:</strong> The endurance capacity was increased by 2.7-fold in the supplemented trainees as compared to the unsupplemented swim trainees which showed an increase by 1.9 fold by the end of 9 weeks compared to the first week. Plasma lactate showed a significant reduction by 25% and 37% in swim trained and supplemented trainees compared to the sedentary. The haemoglobin level showed an increase in the swim trained rats by 19% and 28% in the supplemented trainees compared to the sedentary animals. The packed cell volume increased in swim trained rats by 10% and 19% in the supplemented trainees compared to the sedentary animals. Supplemented trained rats showed a reduction in total cholesterol by 13 % and 15.55% in swim trainees with and without supplementation compared to the sedentary rats respectively. The catalase activity exhibited a significant change in supplemented trainees compared to the sedentary by 20% in Soleus and 71% in extensor digitorum longus compared with the respective sedentary muscle and by 7.5% and 28% compared to the unsupplemented trainees. <strong>Conclusion: </strong>In conclusion, grape seed extract reduces oxidative stress by increasing antioxidant enzymes activity.</p>}, number={2}, journal={Free Radicals and Antioxidants}, author={Ahmad Tantry, Towseef and Ahmad Wani, Nazir}, year={2021}, month={Jan.}, pages={69–76} }