@article{Bisen_Chaturvedi_Ganeshpurkar_Dubey_2020, title={Cardioprotective Effect of Ethanolic Extract of Leaves of Amaranthus cruentus in Isoprenaline-Induced Myocardial Infarction in Rats}, volume={10}, url={https://www.antiox.org/index.php/fra/article/view/10}, DOI={10.5530/fra.2020.1.5}, abstractNote={<p><strong>Objectives:</strong> The present study is focused to evaluate cardioprotective activity of ethanolic extract of <em>Amaranthus cruentus</em>. <strong>Methods:</strong> <em>Amaranthus cruentus</em> extract (Dose 200mg/kg and 400mg/kg) in isoprenaline induced myocardial infarction in rats. The ethanolic extract of<em> Amaranthus cruentus</em> was prepared and subjected to acute toxicity in albino rats. The extract was given orallyat two different doses 200mg/kg and 400mg/. Isoprenaline was administered subcutaneously (85mg/kg s.c.). <strong>Results:</strong> The histopathological examination revealed mild infarction and inflammation in isoprenaline treated rats. The ethanolic extract of <em>Amaranthus cruentus</em> showed significant cardio protective effect by decreasing the serum level of LDL and VLDL cholesterol levels. The biochemical parameters (AST, ALT and ALP) and HDL cholesterol levels were restored. <strong>Conclusion:</strong> The outcome of the present study suggested cardioprotective activity of <em>Amaranthus cruentus</em> extract.</p>}, number={1}, journal={Free Radicals and Antioxidants}, author={Bisen, Priya and Chaturvedi, Aman and Ganeshpurkar, Aditya and Dubey, Nazneen}, year={2020}, month={Aug.}, pages={24–28} }