Wound Healing Activity of Herbal Ointment Containing the Extracts of Hibiscus rosa-sinensis Flowers and Curcuma longa Rhizomes

Authors

  • Fazlina Mustaffa Department of Pharmacology, Faculty of Pharmacy, Asian Institute of Medical Sciences and Technology (AIMST) University-Kedah, MALAYSIA.
  • Subramani Parasuraman Department of Pharmacology, Faculty of Pharmacy, Asian Institute of Medical Sciences and Technology (AIMST) University-Kedah, MALAYSIA.
  • Geethaa Sahgal Department of Pharmaceutical Technology, Faculty of Pharmacy, Asian Institute of Medical Sciences and Technology (AIMST) University-Kedah, MALAYSIA.

DOI:

https://doi.org/10.5530/fra.2020.2.15

Keywords:

Hibiscus rosa-sinensis, Curcuma longa, Wound healing

Abstract

Objectives: To evaluate wound healing activity of herbal ointment containing the extracts of Hibiscus rosa-sinensis flowers and Curcuma longa rhizomes. Methodology: H. rosa-sinensis flowers and C. longa rhizomes were extracted using 95% ethanol. H. rosa-sinensis and Hibiscus rosa-sinensis ointment were prepared using paraffin wax, lanolin and petroleum jelly. Ointment formulation was applied once daily on the excision wound made on Sprague Dawley rats for 20 days. Results: On day 20, the treatment group showed a significant increase in wound contraction which was 93.52 ± 1.38% when compared to control (87.62 ± 1.48%). Conclusion: Herbal ointment exhibited significant wound healing activity in rat excision wound model.

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Wound Healing Activity of Herbal Ointment Containing the Extracts of Hibiscus rosa-sinensis Flowers and Curcuma longa Rhizomes

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Published

2021-01-29

How to Cite

Mustaffa, F. ., Parasuraman, S. ., & Sahgal, G. . (2021). Wound Healing Activity of Herbal Ointment Containing the Extracts of Hibiscus rosa-sinensis Flowers and Curcuma longa Rhizomes. Free Radicals and Antioxidants, 10(2), 86–88. https://doi.org/10.5530/fra.2020.2.15