Synthesis of Schiff base Metal Complexes with Motivating Scavenging Potential Studies


Free Radicals and Antioxidants,2019,9,1,xx-xx.
Published:January 2019
Type:Research Article
Author(s) affiliations:

Khalida Al-Azawi1, Dunya Lafta AL-Duhaidahawi2, Ahmed Al-Amiery3,*, Abdul Amir Hassan Kadhum4

1Department of Applied Science, University of Technology, Baghdad, IRAQ.

2Pharmacy school, Kufa University, Kufa, IRAQ.

3Energy and Renewable Energies Technology Center, University of Technology, Baghdad, IRAQ.

4Department of Chemical and Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, Bangi, Selangor 43600, MALAYSIA.


Objective: Schiff’s base complexes can be important substitutes for some antioxidant drugs because they have a carbon-nitrogen (N-C) double bond with the ability to push the electrons into the transition metal. Methods: A series of Schiff base metal complexes have been synthesized by the condensation of MCl2.nH2O (M = Co, Ni, Cu) with 1-(2hydroxybenzylideneamino) quinolin-2(1H)-one. Results: The Schiff base and it metal complexes have been characterized by various instrumental techniques like element chemical analysis, molar conductance, magnetic susceptibility measurements and spectral studies. The investigated complexes were subjected to antioxidant studies. The investigated complexes showed an excellent activities as antioxidant as compared to the parent Schiff base and standard compound. Conclusion: The data showed that transition metal complexes have significant improved antioxidant activity than Schiff base.