Antioxidant Assay of Gold and Silver Nanoparticles from Edible Basidiomycetes Mushroom Fungi

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Abstract
Free Radicals and Antioxidants,2017,7,2,137-142.
Published:March 2017
Type:Original Article

Antioxidant Assay of Gold and Silver Nanoparticles from Edible Basidiomycetes Mushroom Fungi

Rajendran Madhanraj1, Muthukumarasamy Eyini2, Paulraj Balaji1*

1PG and Research Centre in Biotechnology, MGR College, Hosur – 635130, Tamilnadu, INDIA.

2Centre for Research and PG studies in Botany, Thiagarajar College, Madurai - 625009, Tamilnadu, INDIA.

Abstract:

Background: In recent years, nanotechnology research is emerging as cutting edge technology interdisciplinary with physics, chemistry, biology, material science and medicine. AuNPs and AgNPs are an important class of nanomaterial for a wide range of biomedical applications. Synthesis of AuNPs and AgNPs through biological route is preferred due to its environment-friendly and economic aspects. Mushrooms have been known for their nutritional values and used as medicines by humans for ages. In modern terms, they can be considered as functional foods which can provide health benefits beyond the traditional nutrients. The present study demonstrates an eco-friendly and low-cost method of biosynthesis of AuNPs and AgNPs using basidiomycetes mushroom fungal strains. Materials and Methods: The antioxidant potential of the basidiomycetes mushroom fungal strains was analysed by total flavonoid content, FRAP assay, ABTS assay, Metal chelating activity, Phosphomolybdenum assay, Assay of superoxide radical scavenging activity, Free radical scavenging activity on DPPH along with the determination of total phenolic and tannin contents in the mushroom mycelial extracts. Results: The synthesized gold nanoparticles (AuNPs) silver nanoparticles (AgNPs) were confirmed by the colour transformation and Ultraviolet-visible (UV-visible) spectroscopy. These biologically synthesized AuNPs and AgNPs were tested for antioxidant activities. The biosynthesized AuNPs and AgNPs showed significantly higher antioxidant activity. Conclusion: The present study explored that the mushrooms which are efficient producers of AuNPs and AgNPs, and could act as safe and cost-effective with potential antioxidant activities. These findings encourage studying these fungal strains further for their potential biological applications.

Cite This Article

Vancouver Style :: Madhanraj R, Eyini M, Balaji P. Antioxidant Assay of Gold and Silver Nanoparticles from Edible Basidiomycetes Mushroom Fungi. Free Radicals and Antioxidants. 2017;7(2):137-142.  (363.51 KB)
MLA Style: Madhanraj R, Eyini M, Balaji P. Antioxidant Assay of Gold and Silver Nanoparticles from Edible Basidiomycetes Mushroom Fungi. Free Radicals and Antioxidants. 2017;7(2):137-142.  (363.51 KB)
CSE Style: Madhanraj R, Eyini M, Balaji P. Antioxidant Assay of Gold and Silver Nanoparticles from Edible Basidiomycetes Mushroom Fungi. Free Radicals and Antioxidants. 2017;7(2):137-142.  (363.51 KB)
APA Style: Madhanraj R, Eyini M, Balaji P. Antioxidant Assay of Gold and Silver Nanoparticles from Edible Basidiomycetes Mushroom Fungi. Free Radicals and Antioxidants. 2017;7(2):137-142.  (363.51 KB)

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Founded:  In 2004, as the PHCOG.NET – a non-profit private organization dedicated to Natural Products Research leading to develop promising drugs. Our main mission is to make information on herbal drug research readily available in different formats to suit the individual needs. About Journal : Free Radicals and Antioxidants [ISSN: 2231-2536] is an online peer reviewed publication dedicated to publishing novel, original findings in the field of free radical biology and both natural and synthetic antioxidants. Free radicals, which are defined as molecules containing one or more unpaired electrons in their outmost atomic or molecular orbital have emerged as double edged swords.The Free Radicals and Antioxidants Journal aims to foster the dissemination of scientific information by publishing manuscripts that provide new insights into the biology of free radicals, including their generation, degradation, modulation, role in cellular function and cell signaling. The submission of uninvited expert reviews and research articles in all areas of Free Radical Biology and Antioxidants are also welcomed. Free Radicals and Antioxidants publishes full research papers presenting original, high quality research, critical review articles providing comprehensive analysis of research development within a defined area and editorial commentaries on key topical issues in Free Radical and Antioxidant Biology.
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