Analysis of Brazilian Plant Extracts as Potential Source of Antioxidant Natural Products Using Bench-Top Assays


Free Radicals and Antioxidants,2018,8,2,120-129.
Published:April 2018
Type:Original Article

Analysis of Brazilian Plant Extracts as Potential Source of Antioxidant Natural Products Using Bench-Top Assays

Lucyana C. Marin1, Ellen C.M. Cavarsan1, Ingrit E.C. Díaz2, Mateus L.B. Paciencia3, Sergio A. Frana3, Ivana B. Suffredini1,3*

1Graduate Program in Environmental and Experimental Pathology, Paulista University, R. Dr. Bacelar, 1212, Vila Clementino, São Paulo, SP, 04026-002, BRAZIL.

2Facultad de Ingeniería Química y Textil de la Universidad Nacional de Ingeniería, Av. Tupac Amaru 210, Rimac, Lima, PERÚ.

3Graduate Program in Dentistry and Center for Research in Biodiversity, Paulista University, Av. Paulista, 900, 1 andar, São Paulo, SP, 01310-100, BRAZIL.


Introduction: The present work reported the antioxidant and chemical screening of Brazilian plant aqueous and organic extracts. Methods: An amount of 895 Brazilian Amazon aqueous and organic plant extracts were tested in thin layer chromatography plates (TLC) using 2, 2-diphenyl-1-picrylhydrazyl (DPPH), β-carotene, Dragendorff’s reagent, Kedde’s reagent, and KOH reagent so as to evaluate antioxidant activity and chemical profiles. Antioxidant and DPPH free radical scavenging activities results were submitted to chi-square analyses. Results: Only 8.60% of the extracts showed β-carotene/bleaching response, while 96.09% of the extracts responded as a radical scavenger, alkaloids occurred in 8.0% of the extracts whereas anthraquinones occurred in 0.89% of the extracts and cardenolides in 3.89% of the extracts. Conclusion: Present findings described that Amazon plant extracts have a huge potential to be a source of antioxidant compounds to be used in preventive medicine, as well as the chemical screening revealed that their plants can be strategically assessed as a source of alkaloids to be tested in further biological assays.

About Journal

Founded:  In 2004, as the PHCOG.NET – a non-profit private organization dedicated to Natural Products Research leading to develop promising drugs. Our main mission is to make information on herbal drug research readily available in different formats to suit the individual needs. About Journal : Free Radicals and Antioxidants [ISSN: 2231-2536] is an online peer reviewed publication dedicated to publishing novel, original findings in the field of free radical biology and both natural and synthetic antioxidants. Free radicals, which are defined as molecules containing one or more unpaired electrons in their outmost atomic or molecular orbital have emerged as double edged swords.The Free Radicals and Antioxidants Journal aims to foster the dissemination of scientific information by publishing manuscripts that provide new insights into the biology of free radicals, including their generation, degradation, modulation, role in cellular function and cell signaling. The submission of uninvited expert reviews and research articles in all areas of Free Radical Biology and Antioxidants are also welcomed. Free Radicals and Antioxidants publishes full research papers presenting original, high quality research, critical review articles providing comprehensive analysis of research development within a defined area and editorial commentaries on key topical issues in Free Radical and Antioxidant Biology.
Distinctions:  The most widely read, cited, and known Free Radicals and Antioxidants and website is well browsed with all the articles published. More than 20,000 readers in nearly every country in the world each month
Editorial Board
Subjects Covered : Natural Products, Free Radical Biology, Antioxidants
ISSN : 2231-2536 ; Frequency : Half Yearly - Rapid at a time publication (2 issues/year)
Indexed and Abstracted in : Chemical Abstracts, Excerpta Medica / EMBASE, Google Scholar, CABI Full Text, Ulrich’s International Periodical Directory, ProQuest, Journalseek & Genamics, PhcogBase, EBSCOHost, Academic Search Complete, Open J-Gate, SciACCESS.
Rapid publication: Average time from submission to first decision is 30 days and from acceptance to In Press online  publication is 45 days.
Open Access Journal: Free Radicals and Antioxidants is an open access journal, which allows authors to fund their article to be open access from publication.