Analysis of Brazilian Plant Extracts as Potential Source of Antioxidant Natural Products Using Bench-Top Assays

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Abstract
Free Radicals and Antioxidants,2018,8,2,120-129.
Published:April 2018
Type:Original Article
Authors:
Author(s) affiliations:

Lucyana C. Marin1, Ellen C.M. Cavarsan1, Ingrit E.C. Díaz2, Mateus L.B. Paciencia3, Sergio A. Frana3, Ivana B. Suffredini1,3*

1Graduate Program in Environmental and Experimental Pathology, Paulista University, R. Dr. Bacelar, 1212, Vila Clementino, São Paulo, SP, 04026-002, BRAZIL.

2Facultad de Ingeniería Química y Textil de la Universidad Nacional de Ingeniería, Av. Tupac Amaru 210, Rimac, Lima, PERÚ.

3Graduate Program in Dentistry and Center for Research in Biodiversity, Paulista University, Av. Paulista, 900, 1 andar, São Paulo, SP, 01310-100, BRAZIL.

Abstract:

Introduction: The present work reported the antioxidant and chemical screening of Brazilian plant aqueous and organic extracts. Methods: An amount of 895 Brazilian Amazon aqueous and organic plant extracts were tested in thin layer chromatography plates (TLC) using 2, 2-diphenyl-1-picrylhydrazyl (DPPH), β-carotene, Dragendorff’s reagent, Kedde’s reagent, and KOH reagent so as to evaluate antioxidant activity and chemical profiles. Antioxidant and DPPH free radical scavenging activities results were submitted to chi-square analyses. Results: Only 8.60% of the extracts showed β-carotene/bleaching response, while 96.09% of the extracts responded as a radical scavenger, alkaloids occurred in 8.0% of the extracts whereas anthraquinones occurred in 0.89% of the extracts and cardenolides in 3.89% of the extracts. Conclusion: Present findings described that Amazon plant extracts have a huge potential to be a source of antioxidant compounds to be used in preventive medicine, as well as the chemical screening revealed that their plants can be strategically assessed as a source of alkaloids to be tested in further biological assays.